Mirjana Janeček was a student at the Duncan School and completed a four-year dance course at Machanova-Rabasova in Prague. During her studies in Prague, she visited Zagreb from 1922 onward and gave solo dance concerts.

According to a preserved program from the archives of the Croatian Music Institute, it is certain that she performed in Zagreb as a solo dancer—as well as the author and choreographer of her program—as early as 1923. Based on this, the oldest known document to date, it appears that Mirjana Janeček was the first artist in Croatia to express contemporary dance.

In 1930, she opened a state-approved school for artistic dance culture. She developed her own distinctive approach to theatrical dance, which she called living plastic and embodied music. This method consisted of movements accompanied by music, speech, or song, structured according to the principles of statics and dynamics in the artistic representation of the human body.